Human pathogenic bacteria have evolved an "invisibility cloak" which allows them to go undetected by the human immune system. This "invisibility cloak" is similar to what our own cells use to avoid immune attack.
Invizius has identified and isolated this "invisibility cloak", and can manufacture it using standard, industry methods.
By attaching the cloak to man-made medical device surfaces in contact with the blood, Invizius has created H-Guard®, an advanced hemocompatible coating capable of preventing, at source, the blood's foreign body reactions.
H-Guard® is a potent anti-inflammatory and anti-coagulant.
Hollow fibres are now the gold standard in hemocompatible membranes for dialyzers and oxygenators. However, even the highest hemocompatibility now available cannot exclude that extra-corporeal blood circulation over membranes may produce subclinical thromboinflammatory reactions and thus an increased patient risk of cardiovascular, respiratory and other complications.
The application of H-Guard® Priming Solution to the hollow fibres, and other blood contact surfaces of the extra-corporeal circuit, aims to reduce the thromboinflammatory effect on the patient's blood, and to reduce unwanted coagulation.